The project leader, Dr. Eric Allemand, in the group of Dr. Olivier Hermine at the Imagine Institute in Paris, is seeking an engineer (Ingénieur d’étude) with a bioinformatics profile.

OUR TEAM:

Our research is dedicated to investigating the dysregulation of RNA processing mechanisms associated with hematopoietic disorders.

We focus on unraveling splicing dysregulation using Third-Generation Sequencing (TGS) technologies.

Our work has revealed an overlooked diversity in the transcriptome that is not currently assessed in the pathological context through conventional genetic analyses.

Our goal is to identify novel pathological markers linked to splicing and polyadenylation defects, explore their functional impacts, and develop corrective tools to address these diseases.

ROLE AND RESPONSIBILITIES:

The selected candidate will contribute to several cutting-edge projects by operating both homemade and established pipelines to analyse data derived from long-read sequencing, with a particular focus on Oxford Nanopore technology.

The candidate will collaborate with other lab members, particularly PhD students.

REQUIREMENTS :

The ideal candidate should be proficient in several programming languages, including Python, R, and Bash, and possess the ability to perform standard biostatistical analyses.

Experience with bioinformatics workflows and a solid understanding of genomics are highly desirable.

POSITION DETAILS:

The position is for 1 year with a possible extension.

The employment is planned to start immediately or upon agreement with the chosen candidate.

Fixed term contract for 12 months, possibility of extension.

Salary according to experience.

APPLICATION PROCESS :

Candidates are encouraged to send applications in English or French, including:

• Cover letter ;

• Detailed CV with publication list ;

• Contact information for two references.