Context 

The Data Analysis Core facility (DAC) is a core facility of the Paris Brain Institute that supports researchers in the discovery of new insights and treatments in the field of neurological diseases and disorders. The DAC consists of an enthusiastic interdisciplinary team of experts in biostatistics, bioinformatics, image analysis, and data managers. We accompany researchers throughout the research cycle, by providing robust and reproducible analyses, expert advice, training, and the development of new solutions for emerging technologies. If you are interested in the brain and want to contribute to discoveries in a stimulating research environment, the DAC could be the place for you. 
 
Job description  

We are looking for an experienced bioinformatician to reinforce our ability to tackle the questions of today. The fast-evolving field requires initiative to find solutions, and a sensitivity to quality control, communication with research teams, and teamwork. Technical expertise and experience in several omics modalities are needed to meet the increasingly complex and multimodal bioinformatics approaches.  
 
As a member of our omics analysis team, you will be responsible for the translation of biological questions into actionable insights through bioinformatics analyses. Your main tasks will be to: 
 

• Provide support to research teams in the analysis and interpretation of (multi)omics data, including (but not limited to) scRNAseq and Spatial Transcriptomics. 
• Participate in developments of bioinformatics pipelines and workflows for (multi)omics data analysis, ensuring accuracy, reproducibility, and scalability. 
• Collaborate with computational biologists, geneticists, and clinicians to integrate (multi)omics data and facilitate translational research efforts. 
• Stay updated with the latest advancements in omics technologies, bioinformatics tools, and analytical methods, and contribute to the continuous improvement of data analysis workflows. 

 
You will be expected to be independent in managing multiple projects simultaneously, ensuring quality through regular rapports and communication with research teams under the supervision of our omics team manager and supported by the team’s project manager.

• Minimum Bac+5 (master or engineer) in bioinformatics, or equivalent level in biology/computing.  

Know-how  

• Proven expertise in the analysis of single-cell transcriptomics and/or spatial transcriptomics. 
• Proven experience in communicating and interpreting results for researchers/biologists. 
• Proficiency in UNIX environments (shell). 
• Proficiency in R (required), and Python (desired), in a version-controlled setting (Git). 
• Proficiency in data visualization. 

Knowledge  

• Professional experience of at least four years in the field of omics analysis in academia or industry. 
• Training in omics analyses, including but not limited to, batch effect correction, differential expression, pathways enrichment, trajectory analyses, and deconvolution. 
• Academic reading, writing, and conversational skills in English (required) and French (required). 

Soft skills  

• Ability to work in a team according to common procedures. 
• Autonomy, initiative, and flexibility in finding solutions for new and unexpected issues. 
• Ability to communicate with people from various scientific and technical backgrounds. 
• Motivation to advance research in neuroscience!  

Conditions 
Permanent Contract 

Please send your CV and letter of motivation (in English), to stephen.whitmarsh@icm-institute.org with the subject: “Engineer bioinformatics / bioinformatician (F/M) ”